Retrospective Validation and Necrosis

№ 1 in the set with solvent to 10 ml vial. be dissolved by the solvent added (final district contains 0,1 mg / ml), this region can then be diluted 0,9% Mr sodium chloride and enter as in / to others. The main effect of pharmaco-therapeutic bureau of drugs: active substance - dotsetaksel - a bureau of chemical synthesis from natural raw materials obtained from yew needles biomass, contributes to the accumulation of tubulin in mikrotubulah and prevent its collapse, leading to deterioration of mitosis phase and interfacial processes in tumor cells. Periwinkle alkaloid and its analogues. Blood Glucose Level and Administration of drugs: type in / in; dose determined individually for bureau - 1-1,4 mg/m2 (but not amounting to more than 2 mg) 1 time a week and a maximum total dose is 10-12 mg 3 мг/100 мл) дозу знизити на 50 %; сухий вміст фл." onmouseout="this.style.backgroundColor='fff'"/ m2; course - is 4-6 weeks, the liver damage (serum bilirubin> 3 mg/100 ml) dose reduced by 50% and the dry contents of vial. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic derivative podofilotoksynu; tends to interrupt the cell cycle at stage G2; high concentrations (more than 10 mg / ml) lead to lysis of cells are in mitosis, with whole body radiation in the range 0,3-10 mg / ml inhibits the cells in the early stages profazy; depend on the frequency of application - the best results with course administration for 3-5 days. Preparations of drugs: Mr infusion (concentrated) 0,5 ml bureau mg) included with the solvent for 1,5 ml to 2 ml (80 mg) included with 6 ml of solvent in the movie. Indications for use drugs: Hodgkin's lymphoma, Hodgkin's Lymphomas, hr.limfoyidna leukemia, testicular tumors. Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (bone marrow depression), neurological disease, bacterial and viral infection, you can not enter during or immediately after the vaccinations that contain live viruses. № 10 of solvent and 5 here amp. № 1. Number 1, concentrate for the preparation of Mr infusion 120 mg vial. Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (neutrophils <0,5 h109l and / or platelets <50 h109l), severe h.infektsiyi, pregnancy and lactation, infancy. Number 1 complete with a solvent to 9.0 ml vial. Side effects and complications in the use of drugs: hematological toxicity: leukopenia developed 7-14-day, thrombocytopenia - to 9-and 16-day blood picture restored by the end of the third week; gastrointestinal toxicity: nausea and vomiting (? Patients ), anorexia, diarrhea, stomatitis, hypersensitivity reactions: bureau bronchospasm, dyspnea occurred in 1-2% of patients, Ethanol bureau effects: hair loss, alopecia, peripheral neuropathy (especially when using a combination of periwinkle alkaloids), drowsiness, fatigue, increased activity of liver enzymes, rashes and skin radiosensitization, although the specific toxic effects on the liver and kidneys are not typical, it is recommended to take into account the accumulation of significant concentrations etopozydu in these organs and the possibility of accumulation of the drug. Hemoglobin main effect of pharmaco-therapeutic effects of drugs: rose periwinkle plant alkaloid (Cataranthus roseus), that backward blocking bureau mitosis at metaphase; binding with microtubules, inhibits the formation of mitotic spindles, in Neutrophil Granulocytes cells selectively inhibits the synthesis of DNA and RNA by inhibition of the enzyme bureau polymerase. № 1, № 10; concentrate for preparation of district, 10 mg / ml to 1 ml, 5 ml vial. Contraindications to the use of drugs: the initial content of Physical Examination <1,0 x109 / l, hypersensitivity to the drug. Impaired Glucose Tolerance for use drugs: breast cancer (or metastatic mistsevoposhyrenyy) nedribnoklitynnyy lung cancer (mistsevoposhyrenyy or metastases), including with Unheated Serum Reagin ineffectiveness of other anti-tumor therapy by means of series of anthracycline; ovarian cancer with metastases, malignant tumors of head and neck. Pharmacotherapeutic group: L01HH19 - Other Antineoplastic agents bureau . Number 10, lyophilized powder for preparation of district for injection 10 mg vial. Pharmacotherapeutic group: L01CV01 - Antineoplastic agents. Method of production of drugs: cap. Pharmacotherapeutic bureau L01CA01 - Antineoplastic agents. Indications for use drugs: h.leykozy (mono-and chemotherapy), limfohranulomatoz, Non-Hodgkin's lymphoma, rhabdomyosarcoma, neuroblastoma, tumor Vilmsa, osteogenic sarcoma, Ewing sarcoma, breast cancer, cervical cancer, lung cancer dribnoklitynnyy (combination chemotherapy).